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Steroids in covid-19 pneumonia
New studies confirm that multiple types of steroids improve survival for severely ill COVID-19 patients, cementing the cheap drugs as a'first line' of treatment for COVID-19 patients.
This new data, published today in The American Journal of Physiology, supports earlier research suggesting that steroids, which are highly prescribed for treating COVID-19 patients, may improve survival of these patients by preventing the progression of disease and improving the quality of life, steroids in dubai pharmacy.
"This provides strong evidence that the use of steroids for COVID-19 patients is beneficial and that steroid hormones could be used as a first-line treatment for this disease," says co-first author Soren Svidberg, M, steroids in covid-19 pneumonia.D, steroids in covid-19 pneumonia., lead investigator of the study and an associate professor of medicine at The Ohio State University Wexner Medical Center in Columbus, steroids in covid-19 pneumonia. He is also a professor of kinesiology and a member of the department of pharmacology, pneumonia steroids covid-19 in.
In their study, Svidberg and colleagues compared survival and quality of life of COVID-19 patients using multiple classes of steroids—ostensibly those that improve cardiac function and reduce cholesterol levels—based on two different methods that have been developed to compare the effectiveness of multiple classes of medicated drugs (see "Study: Astute, Steroid-Based Steroid Medications Are More Effective Than Drug Therapy").
The two methods are the use of structured clinical trials and the use of observational studies, steroids in south korea. Both methods have shown improvement in cardiac function and cholesterol levels, but there have been mixed results based on data from observational studies.
One of those studies used an observational approach in which patients were randomly assigned to either a drug that improved heart function or a drug that does not improve heart function. In contrast, Svidberg and colleagues designed a structured observational study of COVID-19 patients for the purpose of detecting a difference between the treatment conditions.
To determine whether the use of multiple drugs improved survival and quality of life, the investigators compared 18 COVID-19 patients enrolled in two groups. In the randomized study of COVID-19 patients (12% of whom were taking steroids), steroid patients had higher survival rates, improved survival outcomes, and improved quality of life than the drug-naïve non-steroid patients.
The investigators also observed a greater improvement in disease progression in steroid-initiated patients compared with steroid-naïve patients.
Svidberg says that the improved data provide strong, new evidence that steroid-induced improvements in cardiac function and cholesterol levels are protective for COVID-19 patients and may lead to improved survival of patients with COVID-19, steroids in body naturally.
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